Every 1% Reduction in A1C Results in 40% Reduction in Risk of Developing Eye, Kidney, and Nerve Disease; and a 21% Decrease in Death Related to Diabetes

DarioHealth reduces A1C by up to 2.3%

By: João Mendes-Roter, Vice-President of Marketing at DarioHealth

 

Mobile devices and big data are immensely powerful tools when applied to patient education for the management of chronic conditions like diabetes. The convergence that is happening today between healthcare and mobile digital platforms is saving lives, saving money, and improving quality of life for people living with chronic conditions.

DarioHealth’s  digital diabetes care delivery platform, a leading solution in its category, has regulatory approval in the U.S. and six other countries where over 48 million people can benefit from the mobile-phone based solution that provides real-time data and coaching. Data published1 this year at the American Diabetes Association (ADA) showed that DarioHealth’s platform improved patient outcomes and reduced A1C by up to 2.3% in high A1C patients over 9 months, creating cost savings of $80 – $230 per month, based on a study of more than 17,000 people who were using the DarioHealth platform.

Savings created by DarioHealth are a very welcome and positive development in the face of skyrocketing healthcare costs associated with diabetes.

Last year in the U.S., direct medical costs for diabetes amounted to $237 billion according to the American Diabetes Association2. On an inflation adjusted basis, the economic cost of treating diabetes jumped 26% between 2012 and 2017.

DarioHealth is reversing this trend through its market leading digital health solutions which reduce A1C by between 1% – 2.3%.

A1C,  or glycated hemoglobin, is a measure of the amount of sugar that is coating red blood cells. It is the best indicator of how well diabetes is being managed over time because it provides a 3-month average of blood sugar levels, as compared to a static reading from one point in time from a finger prick test.

People without diabetes have A1C levels of 4-6%. For people with diabetes, A1C of less than 7% is desired to help reduce the risk of complications. However, approximately half of people living with diabetes have A1C of greater than 7%.

Each 1% Decrease in A1C is Associated with Significant Reduction in Life-Threatening Complications of Diabetes

Rising A1C levels cause microvascular damage which leads to kidney failure, blindness, and lower-limb amputations. According to a Harvard study3, 44% of all kidney failure cases in the U.S. were caused by diabetes, while 73,000 lower-limb amputations in the U.S. were performed per year on adults living with diabetes.

A1C takes its toll on human life and wellbeing. Reductions in A1C, as created by DarioHealth, can have a tremendous beneficial impact.

“In general, for every 1% reduction in results of A1C blood tests (e.g., from 8.0% to 7.0%), the risk of developing eye, kidney, and nerve disease is reduced by 40%,”4 according to the U.S. Centers for Disease Control.

A report from the Center for Health Law and Policy Innovation of Harvard Law School advocates for “disease self-management education”5, concluding that based on cost-benefit analyses, patient education in diabetes should be provided by insurers because it will lead to lower costs and improve patient health.  Better self-management reduces A1C levels. The Harvard report indicates that a 1% reduction of A1C is associated with a 37% decrease in microvascular complications, a 14%  reduction in myocardial infarction, and a 21% decrease in death  related to diabetes.

Disease self-management education is exactly what DarioHealth’s platform delivers. By providing actionable, real-time data, coupled with coaching and patient education, all delivered through the patient’s  mobile phone, DarioHealth’s digital  health solutions empower patients to optimize their self-care.

“Benefits to the user are clear, as evidenced both in the quantitative data we have gathered, as well as through the qualitative data we receive daily from users who inform of us improvements in their wellbeing. We have created a supportive online community and real-time connectivity with care givers that is a positive feedback loop for patients that rewards self-care,” stated DarioHealth CEO Erez Raphael.

Substantial Financial Benefits Result From Each 1% Reduction in A1C

The high financial costs associated with complications from diabetes is well documented. Results from a four-year long study published in Diabetes Care underscores the very high financial impacts of just a 1% increase in A1C.

For every 1% increase in A1C over normal levels, health care costs increased by 4% (A1C of 7%), 10% (A1C of 8%), 20% (A1C of 9%), and 30% (A1C of 10%).  The study concluded, “The medical charge data suggest that investment in clinical systems to improve diabetes care may benefit both payers and patients.”6

“We are seeing a growing movement among payers, including employers and insurers, who see the economic incentive to pay for digital health solutions like ours,” said Raphael. “DarioHealth is gaining increasing traction with our DarioEngage platform, which integrates with healthcare providers’ internal systems to deliver patient coaching based on real-time data and analytics.”

One healthcare provider closely watching the correlation between A1C levels and medical costs, Geisinger Health System7, estimates a 1% reduction in A1C saves them $8,000 per year for the person insured. A broader study from Diabetes in Control reported that better management of diabetes can reduce cost per patient by an average of $1,328 per month, about $16,000 per year.8

First and foremost, improving patient health is the goal of DarioHealth’s digital health technologies and data reported at the American Diabetes Association show DarioHealth’s solution does exactly that. The secondary benefit of lowered healthcare costs is critical. Lower costs for payers creates economic justification for increased investments in digital health solutions like DarioHealth’s, thus making these highly-effective solutions available to more people living with chronic conditions. DarioHealth has created a broader positive feedback loop, empowering patients to greater levels of self-care and incentivizing payers to provide digital health solutions that reduce healthcare costs.

João Mendes-Roter is DarioHealth’s Vice President of Marketing. She is a marketing executive and online digital expert in growth marketing and direct response. Joao is pleased to apply her digital engagement expertise to improve the health and lives of people living with chronic disease. She has a proven track-record in increasing revenues and costumer experience, via better funnels, new products, effective online-offline marketing channels, and new business opportunities. Prior to joining DarioHealth, she held senior roles at 888 Holdings and gained valuable experience at RadView Software and Dun & Bradstreet.

1 DarioHealth Presents New Data at American Diabetes Association’s 78th Scientific Sessions on June 25, 2018, www.dariohealth.comhttp://mydario.investorroom.com/2018-06-25-DarioHealth-Presents-New-Data-at-American-Diabetes-Associations-78th-Scientific-Sessions-on-June-25-2018

2 American Diabetes Association, http://care.diabetesjournals.org/content/diacare/early/2018/03/20/dci18-0007.full.pdf

3, 5 Center for Health Law and Policy Innovation of Harvard Law School – https://www.diabeteseducator.org/docs/default-source/advocacy/reconsidering-cost-sharing-for-dsme-chlpi-paths-6-11-2015-(final-draf.pdf?sfvrsn=2

4 U.S. Centers for Disease Control https://www.cdc.gov/diabetes/managing/health.html

6 Diabetes Care https://www.ncbi.nlm.nih.gov/pubmed/9405905

7 National Public Radio https://www.npr.org/sections/thesalt/2017/05/08/526952657/fresh-food-by-prescription-this-health-care-firm-is-trimming-costs-and-waistline

8 Diabetes in Control http://www.diabetesincontrol.com/the-true-cost-of-diabetes-and-preventing-it/

About DarioHealth Corp.

DarioHealth Corp. (NASDAQ: DRIO) is a leading global digital health company serving its users with dynamic mobile health solutions. In today’s day and age, knowledge of health and treatment is being democratized, and we believe people deserve to know everything about their own health and have the best tools to manage their condition. DarioHealth employs a revolutionary approach whereby harnessing big data, we have developed a novel method for chronic disease data management, empowering people to analyze and personalize self-diabetes management in a totally new way without having the disease slow them down. DarioHealth has a commercial office in New York with an R&D center in Caesarea, Israel. For more information, visit http://mydario.investorroom.com/.

Cautionary Note Regarding Forward-Looking Statements

This news release and the statements of representatives and partners of DarioHealth Corp. (the “Company”) related thereto contain or may contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Statements that are not statements of historical fact may be deemed to be forward-looking statements. Without limiting the generality of the foregoing, words such as “plan,” “project,” “potential,” “seek,” “may,” “will,” “expect,” “believe,” “anticipate,” “intend,” “could,” “estimate,” or “continue” are intended to identify forward-looking statements. For example, when the Company describes the benefits of its platform, describes potential cost savings, describes its potential user base, and describes potential future revenues, it is using forward-looking statements. Readers are cautioned that certain important factors may affect the Company’s actual results and could cause such results to differ materially from any forward-looking statements that may be made in this news release. Factors that may affect the Company’s results include, but are not limited to, regulatory approvals, product demand, market acceptance, impact of competitive products and prices, product development, commercialization or technological difficulties, the success or failure of negotiations and trade, legal, social and economic risks, and the risks associated with the adequacy of existing cash resources. Additional factors that could cause or contribute to differences between the Company’s actual results and forward-looking statements include, but are not limited to, those risks discussed in the Company’s filings with the U.S. Securities and Exchange Commission. Readers are cautioned that actual results (including, without limitation, the timing for and results of the Company’s commercial and regulatory plans for Dario) may differ significantly from those set forth in the forward-looking statements. The Company undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by applicable law.